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Estuary Biotherapeutics

San Francisco, United States

series-a$93M raisedFreshly fundedBiotechDigital HealthDrug Discovery

◆ Total Raised

$93M

◆ Stage

series-a

◆ Location

San Francisco, United States

◆ Team size

1-10

◆ Links

◆ About Estuary Biotherapeutics

Gene therapy company developing kidney-directed AAV delivery platform for autosomal dominant polycystic kidney disease (ADPKD).

◆ What sets it apart

Its AAV delivery platform is designed for local kidney targeting, enabling gene therapies intended to restore polycystin function across the nephron.

◆ Sectors

BiotechDigital HealthDrug Discoveryrare diseasekidney disease

◆ Business

Modeltransactional

CustomerBiopharmaceutical companies, healthcare investors, clinicians, and patients with inherited kidney diseases

◆ Notable

  • Launched with $103 million in committed financing
  • Raised a $93 million Series A led by RA Capital Management
  • Developed two lead ADPKD gene therapy programs, EST-201 and EST-101

◆ Backing funds on Raise

◆ Funding rounds

16 Oct 2026

Led by RA Capital Management

With Deep Track Capital, Biogen New Ventures, UPMC Enterprises, Pivotal bioVenture Partners, National Kidney Foundation Innovation Fund, 4BIO Capital, GV

Source ↗

◆ Explore the market

◆ FAQ

What does Estuary Biotherapeutics do?

Gene therapy company developing kidney-directed AAV delivery platform for autosomal dominant polycystic kidney disease (ADPKD).

Where is Estuary Biotherapeutics based?

Estuary Biotherapeutics is based in San Francisco, United States.

How much has Estuary Biotherapeutics raised?

Estuary Biotherapeutics has raised $93M in tracked funding and is currently at the series-a stage.

Who has invested in Estuary Biotherapeutics?

Investors in Estuary Biotherapeutics include RA Capital Management, Deep Track Capital, Biogen New Ventures, UPMC Enterprises, Pivotal bioVenture Partners, National Kidney Foundation Innovation Fund, 4BIO Capital and GV.